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Pregabalin capsules 75 mg

Original price was: $200.00.Current price is: $150.00.

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Description

Pregabalin is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder. It is marketed under the brand name Lyrica among others. Pregabalin is a derivative of the neurotransmitter gamma-aminobutyric acid (GABA) and it works by binding to calcium channels in the central nervous system. This binding reduces the release of neurotransmitters such as glutamate, norepinephrine, and substance P, which are involved in pain signaling.

Medical Uses

Pregabalin is primarily used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder. In epilepsy, it may be used for partial onset seizures. For neuropathic pain, it is commonly prescribed for conditions such as diabetic neuropathy, post-herpetic neuralgia, and spinal cord injury. Additionally, pregabalin has been found to be effective in managing fibromyalgia symptoms. It is also approved for the treatment of generalized anxiety disorder.

Mechanism of Action

Pregabalin’s mechanism of action involves its binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding modulates the release of several neurotransmitters including glutamate, norepinephrine, and substance P. By reducing the release of these neurotransmitters, pregabalin exerts its antiepileptic, analgesic, and anxiolytic effects.

Side Effects

Common side effects of pregabalin include dizziness, drowsiness, dry mouth, weight gain, and blurred vision. More serious side effects may include an increased risk of suicidal thoughts or behavior and angioedema. Abrupt discontinuation of pregabalin may result in withdrawal symptoms such as insomnia, headache, nausea, anxiety, hyperhidrosis (excessive sweating), and diarrhea.

Precautions and Contraindications

Pregabalin should be used cautiously in individuals with a history of drug or alcohol abuse due to its potential for abuse and dependence. It is also important to monitor patients for signs of suicidal ideation or behavior while taking pregabalin. Additionally, caution should be exercised when using pregabalin in individuals with heart failure or those taking medications that depress the central nervous system.

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