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Antidolnait 500mg/25mg 10 film-coated tablets is a medication that contains 500mg of paracetamol and 25mg of codeine phosphate. This combination is commonly used for the relief of moderate to severe pain. Paracetamol is a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer). Codeine, on the other hand, is an opioid pain medication that is sometimes combined with other medications to enhance its effectiveness in managing pain.

Composition and Indications

The composition of Antidolnait 500mg/25mg includes paracetamol and codeine phosphate. Paracetamol works by inhibiting the production of prostaglandins in the brain, which are responsible for transmitting pain signals and inducing fever. Codeine, as an opioid, acts on the central nervous system to reduce the perception of pain.

This medication is indicated for the relief of moderate to severe pain, such as that caused by dental procedures, surgery, or injury. It is important to note that this medication should be used with caution and under medical supervision due to the potential for abuse and addiction associated with opioids like codeine.

Dosage and Administration

The recommended dosage of Antidolnait 500mg/25mg is determined by a healthcare professional based on the individual’s age, weight, and the severity of the pain being treated. It is typically taken orally with a full glass of water. It is important to follow the prescribed dosage and not exceed the maximum daily dose to avoid potential adverse effects.

Side Effects and Precautions

As with any medication, Antidolnait 500mg/25mg may cause side effects. Common side effects may include drowsiness, dizziness, constipation, nausea, and vomiting. More serious side effects such as respiratory depression or allergic reactions are rare but possible.

It is crucial for individuals taking this medication to be aware of potential drug interactions, especially with other medications that depress the central nervous system such as alcohol or benzodiazepines. Additionally, individuals with a history of substance abuse or certain medical conditions should use this medication cautiously or under medical supervision.


In conclusion, Antidolnait 500mg/25mg 10 film-coated tablets contain a combination of paracetamol and codeine phosphate and are indicated for the relief of moderate to severe pain. It is essential to use this medication as prescribed by a healthcare professional and be aware of potential side effects and precautions associated with its use.


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